{"id":8277,"date":"2023-09-08T01:47:40","date_gmt":"2023-09-07T16:47:40","guid":{"rendered":"https:\/\/bamboolab.yamasatoagr.com\/?p=8277"},"modified":"2024-04-30T18:14:54","modified_gmt":"2024-04-30T09:14:54","slug":"tca-%e3%82%b5%e3%82%a4%e3%82%af%e3%83%ab%e3%81%ae%e8%a9%b1%e3%81%af%e7%b5%82%e3%82%8f%e3%81%a3%e3%81%9f%e3%81%ae%e3%81%8b%e3%83%bb%e3%83%bb%e3%83%bb7","status":"publish","type":"post","link":"https:\/\/bamboolab.yamasatoagr.com\/?p=8277","title":{"rendered":"\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3078\u306e\u7570\u8ad6\u30fb\u30fb\u30fb\uff15"},"content":{"rendered":"\r\n<p>\u3000\u6b21\u306f\u30c7\u30a3\u30b9\u30b3\u30bb\u30a2\u7db1(class <em>Discosea<\/em>)\u306b\u5c5e\u3059\u308b<em> Acanthamoeba castellanii<\/em> \u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3067\u3042\u308b\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"709\" class=\"wp-image-8278\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/08\/image-12-1024x709.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/08\/image-12-1024x709.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/08\/image-12-300x208.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/08\/image-12-768x532.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/08\/image-12.png 1311w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\r\n<figcaption class=\"wp-element-caption\"><a href=\"https:\/\/www.genome.jp\/pathway\/acan00030\" target=\"_blank\" rel=\"noreferrer noopener\">acan<\/a> <em>Acanthamoeba castellanii <\/em>\u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000<em>Acanthamoeba castellanii<\/em> \u306f\u30a2\u30e1\u30fc\u30d0\u578b\u306e\u539f\u751f\u751f\u7269\u306e\u4e00\u7a2e\u3067\u3001\u6de1\u6c34\u57df\u3084\u305d\u306e\u4ed6\u306e\u5834\u6240\u306b\u3082\u5e83\u304f\u5206\u5e03\u3059\u308b\u571f\u58cc\u5fae\u751f\u7269\u3067\u3042\u308b\u3002\u30a2\u30ab\u30f3\u30c8\u30a2\u30e1\u30fc\u30d0\u5c5e\u306e\u5927\u534a\u306f\u30d0\u30af\u30c6\u30ea\u30a2\u3092\u6355\u98df\u3057\u3066\u751f\u6d3b\u3059\u308b\u5f93\u5c5e\u6804\u990a\u751f\u7269\u3067\u3042\u308b\u304c\u3001\u4e00\u90e8\u306e\u7a2e\u306f\u611f\u67d3\u6027\u3092\u6301\u3061\u3001\u30d2\u30c8\u3084\u4ed6\u306e\u52d5\u7269\u306b\u5bfe\u3057\u3066\u89d2\u819c\u708e\u3084\u8133\u708e\uff08\u30a2\u30e1\u30fc\u30d0\u6027\u8089\u82bd\u816b\u6027\u8133\u708e\uff09\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002\u3053\u306e<em>Acanthamoeba castellanii<\/em> \u3082\u30a2\u30ab\u30f3\u30c8\u30a2\u30e1\u30fc\u30d0\u89d2\u819c\u708e\u3092\u5f15\u304d\u8d77\u3053\u3059\u3089\u3057\u3044\u3002\u3068\u306f\u3044\u3048\u3001<em>Acanthamoeba castellanii<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u306f\u3044\u307e\u307e\u3067\u4f55\u5ea6\u3082\u898b\u3066\u304d\u305f\u3082\u306e\u3067\u3042\u308a\u3001NADPH2\u306e\u307f\u306a\u3089\u305a\u5b8c\u5168\u306a\u5f62\u306e\u7cd6\u76f8\u4e92\u5909\u63db\u7cfb\u3092\u6301\u3064\u30aa\u30fc\u30bd\u30c9\u30c3\u30af\u30b9\u306a\u3082\u306e\u3067\u3042\u308a\u3053\u308c\u4ee5\u4e0a\u306e\u8b70\u8ad6\u306f\u4e0d\u8981\u3067\u3042\u308d\u3046\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u6b21\u306f\u539f\u751f\u751f\u7269\u306e\u5927\u304d\u306a\u30b0\u30eb\u30fc\u30d7\u3067\u3042\u308b\u30a2\u30d4\u30b3\u30f3\u30d7\u30ec\u30c3\u30af\u30b9\u9580\uff08Apicomplexa\uff1b\u307e\u305f\u306f\u30a2\u30d4\u30b3\u30f3\u30d7\u30ec\u30af\u30b5\u985e\uff09\u306b\u5c5e\u3059\u308b\u539f\u751f\u52d5\u7269\u306b\u3064\u3044\u3066\u3067\u3042\u308b\u3002\u30a2\u30d4\u30b3\u30f3\u30d7\u30ec\u30c3\u30af\u30b9\u9580\u306e\u4e0b\u4f4d\u5206\u985e\u306b\u3064\u3044\u3066\u306f\u5206\u5b50\u7cfb\u7d71\u89e3\u6790\u306b\u3088\u308b\u518d\u691c\u8a0e\u304c\u884c\u308f\u308c\u3066\u3044\u308b\u6bb5\u968e\u3067\u3042\u308b\u3002Aconoidasida \uff08\u7121\u30b3\u30ce\u30a4\u30c9\u7db1\uff09\u306f\u5206\u5b50\u7cfb\u7d71\u89e3\u6790\u306e\u5c0e\u5165\u4ee5\u524d\u306b\u5fae\u7d30\u69cb\u9020\u306b\u57fa\u3065\u304d\u8a2d\u5b9a\u3055\u308c\u305f\u3082\u306e\u3067\u3042\u308b\u304c\u3001\u4e3b\u8981\u306a\u751f\u7269\u7fa4\u306b\u304a\u3044\u3066\u306f\u5206\u5b50\u7cfb\u7d71\u89e3\u6790\u3067\u3082\u6bd4\u8f03\u7684\u5b89\u5b9a\u7684\u306a\u30af\u30ec\u30fc\u30c9\u3092\u5f62\u6210\u3059\u308b\u3002\u304a\u305b\u3063\u304b\u3044\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001\u30af\u30ec\u30fc\u30c9\u3068\u306f\u5171\u901a\u306e\u7956\u5148\u304b\u3089\u7a2e\u5206\u5316\u306b\u3088\u308a\u6d3e\u751f\u3057\u305f\u5b50\u5b6b\u306e\u3059\u3079\u3066\u3092\u542b\u3080\u7a2e\u306e1\u7fa4\u3092\u610f\u5473\u3059\u308b\u5206\u5c90\u7fa4\u3092\u3044\u3046\u3002\u30a2\u30d4\u30b3\u30f3\u30d7\u30ec\u30af\u30b5\u985e\u306f\u3001\u751f\u6d3b\u74b0\u306e\u3069\u3053\u304b\u3067\u30a2\u30d4\u30ab\u30eb\u30b3\u30f3\u30d7\u30ec\u30c3\u30af\u30b9\uff08apical complex\u3001\u9802\u7aef\u8907\u5408\u69cb\u9020\uff09\u3068\u3044\u3046\u69cb\u9020\u3092\u6301\u3064\u539f\u751f\u751f\u7269\u306e\u5927\u304d\u306a\u30b0\u30eb\u30fc\u30d7\u3067\u3042\u308b\u3002\u5bc4\u751f\u6027\u3067\u3042\u308a\u3001\u914d\u5076\u5b50\u306e\u6642\u671f\u4ee5\u5916\u306f\u97ad\u6bdb\u3084\u4eee\u8db3\u3092\u6301\u305f\u306a\u3044\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-table\">\r\n<table>\r\n<tbody>\r\n<tr>\r\n<td>Apicomplexa (apicomplexans)<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000Aconoidasida<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000Haemosporida<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pfa00030\">pfa<\/a> Plasmodium falciparum 3D7<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pfd00030\">pfd<\/a> Plasmodium falciparum Dd2<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pfh00030\">pfh<\/a> Plasmodium falciparum HB3<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/prei00030\">prei<\/a> Plasmodium reichenowi<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pgab00030\">pgab<\/a> Plasmodium gaboni<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pyo00030\">pyo<\/a> Plasmodium yoelii<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pcb00030\">pcb<\/a> Plasmodium chabaudi<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pbe00030\">pbe<\/a> Plasmodium berghei<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pvv00030\">pvv<\/a> Plasmodium vinckei vinckei<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pkn00030\">pkn<\/a> Plasmodium knowlesi<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pvx00030\">pvx<\/a> Plasmodium vivax<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/pcy00030\">pcy<\/a> Plasmodium cynomolgi<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000Piroplasmida<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/tan00030\" target=\"_blank\" rel=\"noreferrer noopener\">tan<\/a> Theileria annulata<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/tpv00030\">tpv<\/a> Theileria parva<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/tot00030\">tot<\/a> Theileria orientalis<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/beq00030\">beq<\/a> Theileria equi<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/bbo00030\">bbo<\/a> Babesia bovis<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/bmic00030\">bmic<\/a> Babesia microti<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/bbig00030\">bbig<\/a> Babesia bigemina<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000Conoidasida<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000Eucoccidiorida<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u3000\u3000\u3000<a href=\"https:\/\/www.genome.jp\/pathway\/tgo00030\">tgo<\/a> Toxoplasma gondii<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000\u3000\u3068\u3044\u3046\u4e8b\u3067\u3001\u307e\u305a Haemospororida\uff08\u4f4f\u8840\u80de\u5b50\u866b\uff09\u304b\u3089\u59cb\u3081\u3088\u3046\u3002\u4f4f\u8840\u80de\u5b50\u866b\u306f\u8d64\u8840\u7403\u3084\u767d\u8840\u7403\u306b\u5bc4\u751f\u3059\u308b\u539f\u751f\u751f\u7269\u306e\u4e00\u7fa4\u3067\u3001\u4ee3\u8868\u7684\u306a\u3082\u306e\u306f\u30de\u30e9\u30ea\u30a2\u539f\u866b\u3067\u3042\u308b\u3002\u9678\u4e0a\u810a\u690e\u52d5\u7269\u3092\u4e2d\u9593\u5bbf\u4e3b\u3001\u5438\u8840\u6606\u866b\u3092\u7d42\u5bbf\u4e3b\u3068\u3059\u308b\u5834\u5408\u304c\u591a\u3044\u3002 <em>Plasmodium falciparum<\/em> 3D7\u304b\u3089\u3000<em>Plasmodium cynomolgi<\/em>\u307e\u3067\u300112\u7a2e\u306e\u30de\u30e9\u30ea\u30a2\u75c5\u539f\u4f53\u985e\u306f\u3001\u307b\u307c\u540c\u3058\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3092\u6301\u3064\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"710\" class=\"wp-image-8289\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1024x710.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1024x710.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-300x208.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-768x533.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image.png 1309w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\r\n<figcaption class=\"wp-element-caption\"><a href=\"https:\/\/www.genome.jp\/pathway\/acan00030\" target=\"_blank\" rel=\"noreferrer noopener\">a<\/a><a href=\"https:\/\/www.genome.jp\/pathway\/pfa00030\">pfa<\/a> <em>Plasmodium falciparum 3D7<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-8290\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1-1024x708.png\" alt=\"\" width=\"670\" height=\"463\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1-1024x708.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1-300x207.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1-768x531.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-1.png 1314w\" sizes=\"auto, (max-width: 670px) 100vw, 670px\" \/>\r\n<figcaption class=\"wp-element-caption\"><a href=\"https:\/\/www.genome.jp\/pathway\/pfd00030\">pfd<\/a> <em>Plasmodium falciparum Dd2 <\/em>\u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000\u4e0b\u6bb5\u306b<em>Plasmodium falciparum D<\/em>d2\u306e\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u305d\u308c\u4ee5\u5916\u306e11\u7a2e\u306e\u30de\u30e9\u30ea\u30a2\u75c5\u539f\u4f53\u306f\u3001\u4e0a\u6bb5\u306b\u793a\u3057\u305f <em>Plasmodium falciparum 3D7<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3068\u540c\u3058\u3082\u306e\u3092\u6301\u3063\u3066\u3044\u308b\u3002\u3053\u306e\u7cfb\u3092\u898b\u308c\u3070\u3001NADPH2 \u751f\u5408\u6210\u3082\u3067\u304d\u3066\u3044\u308b\u3057\u30ea\u30dc\u30fc\u30b9\u22125\u2212\u30ea\u30f3\u9178\u306e\u751f\u5408\u6210\u3082\u6a5f\u80fd\u3057\u3066\u3044\u308b\u3002\u5171\u751f\u5fae\u751f\u7269\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u5927\u4e8b\u306a\u907a\u4f1d\u5b50\u306f\u6b8b\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u89e3\u91c8\u3067\u826f\u3044\u3060\u308d\u3046\u3002\u305f\u3060\u3001\u5168\u3066\u306e\u7a2e\u306b\u304a\u3044\u3066\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u306e\u83ef\u3068\u3067\u3082\u8a00\u3046\u3079\u304d\u9175\u7d20\uff08\u500b\u4eba\u7684\u611f\u60f3\u306b\u3059\u304e\u306a\u3044\uff09\u3067\u3042\u308bTransaldolase\u3000(EC 2.2.1.2\uff1aSedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase \uff09\u3092\u6b20\u3044\u3066\u3044\u308b\u306e\u306f\u8208\u5473\u6df1\u3044\u3002\u3053\u306e\u9175\u7d20\u304c\u7121\u304f\u3066\u3082\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u306f\u6a5f\u80fd\u3059\u308b\u306e\u3067\u3042\u308b\u3002\u3053\u306e\u9175\u7d20\u306e\u53cd\u5fdc\u3092\u6709\u6a5f\u96fb\u5b50\u8ad6\u7684\u306b\u30c8\u30ec\u30fc\u30b9\u3067\u304d\u305a\u3001\u9577\u671f\u9593\u60a9\u3093\u3060\u3053\u3068\u3092\u601d\u3044\u51fa\u3057\u3066\u3044\u308b\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u4e0b\u6bb5\u306b\u793a\u3057\u305f<em>Plasmodium falciparum Dd2 <\/em>\u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def \u306b\u304a\u3044\u3066\u306f\u3001Ribose phosphate isomerase\uff08EC 5,3, 1,6: D-ribose-5-phosphate aldose-ketose-isomerase\uff09\u306b\u89e6\u5a92\u3055\u308c\u308b\u53cd\u5fdc\u304c\u6b20\u640d\u3057\u3066\u3044\u308b\u3002EC 2.2.1.2\u3068\u540c\u6642\u306bEC 5,3, 1,6\u3092\u6b20\u3044\u305f\u5834\u5408\u3001\u30ea\u30dc\u30fc\u30b9\u20135\u2013\u30ea\u30f3\u9178\u306e\u751f\u5408\u6210\u304c\u4e0a\u624b\u304f\u3067\u304d\u306a\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3046\u306e\u3060\u304c\u3001\u3053\u306e\u53cd\u5fdc\u306f\u9175\u7d20\u304c\u7121\u304f\u3066\u3082\u5c11\u3057\u3065\u3064\u9032\u3080\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u308f\u308c\u308b\u3002<\/p>\r\n\r\n\r\n<div class=\"wp-block-image\">\r\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"447\" height=\"99\" class=\"wp-image-8291\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-2.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-2.png 447w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-2-300x66.png 300w\" sizes=\"auto, (max-width: 447px) 100vw, 447px\" \/><\/figure>\r\n<\/div>\r\n\r\n\r\n<p>\u3000\u6c34\u4e2d\u3067\u3001\u30ea\u30d6\u30ed\u30fc\u30b9\u20135\u2212\u30ea\u30f3\u9178\uff08\u4e0a\u56f3\u53f3\uff09\u306e1\u4f4d\u3068\uff12\u4f4d\u306e\u9593\u3067\u30b1\u30c8\u2013\u30a8\u30ce\u30fc\u30eb\u7570\u6027\u5316\u304c\u8d77\u3053\u308a1\u4f4d\u306e\u70ad\u7d20\u304c\u30a2\u30eb\u30c7\u30d2\u30c9\u3068\u306a\u3063\u305f\u5f8c\u3001\u3053\u306e\u70ad\u7d20\u539f\u5b50\u30922\u4f4d\u306e\u6c34\u9178\u57fa\u304c\u653b\u6483\u3057\u3066\u9589\u9928\u3059\u308c\u3070\u5de6\u306e\u30ea\u30dc\u30fc\u30b9\u22125\u2212\u30ea\u30f3\u9178\u304c\u751f\u6210\u3059\u308b\u53cd\u5fdc\u306f\u3001\u7cd6\u5316\u5b66\u306b\u304a\u3044\u3066\u306f\u3088\u304f\u8d77\u3053\u308b\u53cd\u5fdc\u3067\u3042\u308b\u3002\u4e21\u5316\u5408\u7269\u306e\u6c34\u4e2d\u306b\u304a\u3051\u308b\u5e73\u8861\u5b9a\u6570\u3092\u7cbe\u67fb\u3059\u3079\u304d\u3060\u3068\u306f\u601d\u3046\u304c\u3001\u3055\u307b\u3069\u306e\u554f\u984c\u304c\u8d77\u304d\u306a\u3044\u53ef\u80fd\u6027\u306f\u3042\u308b\u3060\u308d\u3046\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u6b21\u306f\u30a2\u30d4\u30b3\u30f3\u30d7\u30ec\u30c3\u30af\u30b9\u9580\u7121\u30b3\u30ce\u30a4\u30c9\u7db1\u30d4\u30ed\u30d7\u30e9\u30ba\u30de\u76ee\u306e Theileria \u79d1\u3068Babesia \u79d1\u306e\u751f\u7269\u3067\u3042\u308b\u3002\u904e\u53bb\u304b\u3089\u306e\u5206\u985e\u5b66\u306e\u6d41\u308c\u3067\u3001\u5c0f\u578b\u306e\u30bf\u30a4\u30ec\u30ea\u30a2\u79d1\u3068\u5927\u578b\u306e\u30d0\u30d9\u30b7\u30a2\u79d1\u306b\u5206\u3051\u3066\u306f\u3044\u308b\u304c\u3001\u3053\u308c\u306f\u751f\u7269\u306e\u7cfb\u7d71\u3092\u53cd\u6620\u3057\u3066\u304a\u3089\u305a Babesia \u5c5e\u3084 Theileria \u5c5e\u306f\u591a\u7cfb\u7d71\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u308b\u3002\u4e21\u8005\u3068\u3082\u306b\u30de\u30c0\u30cb\u3092\u7d42\u5bbf\u4e3b\u3068\u3059\u308b\u5bc4\u751f\u866b\u3067\u3001\u5438\u8840\u3055\u308c\u305f\u54fa\u4e73\u52d5\u7269\u3084\u9ce5\u985e\u306e\u8840\u7403\u306b\u5bc4\u751f\u3059\u308b\u539f\u751f\u751f\u7269\u3067\u3042\u308b\u3002 \u71b1\u5e2f\u306b\u304a\u3044\u3066\u5bb6\u755c\u306b\u5bfe\u3059\u308b\u81f4\u6b7b\u7684\u306a\u75c5\u539f\u4f53\u3068\u3057\u3066\u8b66\u6212\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u65e5\u672c\u3067\u3082\u653e\u7267\u725b\u306e\u9593\u3067\u8513\u5ef6\u3057\u3066\u3044\u308b\u5c0f\u578b\u30d4\u30ed\u30d7\u30e9\u30ba\u30de\u75c7\u75c5\u539f\u4f53\u3082\u542b\u307e\u308c\u3066\u3044\u308b\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u306e\u69cb\u6210\u304b\u3089\u898b\u308b\u3068\u3001Theileria \u79d1\u306e4\u7a2e\u3068<em>Babesia bovis<\/em> \u304c\u4e0b\u306b\u793a\u3057\u305f\u540c\u3058\u7d4c\u8def\u3092\u6301\u3063\u3066\u3044\u308b\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"710\" class=\"wp-image-8305\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-4-1024x710.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-4-1024x710.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-4-300x208.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-4-768x532.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-4.png 1310w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\r\n<figcaption class=\"wp-element-caption\"><a href=\"https:\/\/www.genome.jp\/pathway\/tan00030\" target=\"_blank\" rel=\"noreferrer noopener\">tan<\/a> Theileria annulata\u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000\u5148\u306b\u8ff0\u3079\u305f Transaldolase (EC 2.2.1.2\uff1aSedoheptulose-7-phosphate: D-glyceraldehyde-3-phosphate glyceronetransferase \uff09\u3092\u6b20\u3044\u3066\u3044\u308b\u3060\u3051\u3067\u306a\u304f\u30013\u5358\u7cd6\u30014\u5358\u7cd6\u30015\u5358\u7cd6\u30016\u5358\u7cd6\u30017\u5358\u7cd6\u306e\u76f8\u4e92\u5909\u63db\u3092\u62c5\u3063\u3066\u3044\u308b\u7d4c\u8def\u304c\u629c\u3051\u843d\u3061\u3066\u3044\u308b\u3002\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001NADPH2 \u306e\u751f\u5408\u6210\u3082\u3067\u304d\u3066\u3044\u308b\u3057\u30ea\u30dc\u30fc\u30b9\u22125\u2212\u30ea\u30f3\u9178\u306e\u751f\u5408\u6210\u3082\u6a5f\u80fd\u3057\u3066\u3044\u308b\u3002\u3042\u306e\u7406\u89e3\u304c\u96e3\u3057\u304b\u3063\u305f\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u304c\u3001\u305d\u306e\u5b58\u5728\u610f\u7fa9\u3092\u7dad\u6301\u3057\u305f\u307e\u307e\u3053\u3093\u306a\u306b\u7c21\u7d20\u5316\u3067\u304d\u308b\u306e\u304b\u3068\u9a5a\u3044\u3066\u3044\u308b\u3002\u3068\u306f\u3044\u3048\u3001\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3092\u3001\u89e3\u7cd6\u7cfb\u306e\u4e00\u90e8\u3068\u3042\u308f\u305b\u3066\u56de\u8def\u3092\u5f62\u6210\u3057\u3066\u3044\u308b\u3068\u898b\u306a\u3057\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u56de\u8def\u3068\u79f0\u3059\u308b\u5834\u5408\u304c\u3042\u308b\u304c\u3001\u3053\u308c\u3089\u751f\u7269\u306e\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u306f\u6700\u65e9\u56de\u8def\u3092\u5f62\u6210\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u56de\u8def\u3068\u4e91\u3046\u7528\u8a9e\u306f\u9069\u5207\u3067\u306f\u306a\u3044\u3088\u3046\u3060\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u6b21\u306f <em>Babesia microti<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\u3067\u3042\u308b\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"712\" class=\"wp-image-8307\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-5-1024x712.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-5-1024x712.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-5-300x209.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-5-768x534.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-5.png 1313w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\r\n<figcaption class=\"wp-element-caption\"><em>Babesia microti<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000\u3053\u306e\u539f\u866b\u306e\u4e3b\u8981\u306a\u75c5\u539f\u4f53\u4fdd\u6709\u751f\u7269\u306f\u9f67\u6b6f\u985e\u3067\u3042\u308a\u3001\u901a\u5e38\u306f\u30de\u30c0\u30cb\u79d1\u306e\u30b7\u30ab\u30c0\u30cb\u304c\u5a92\u4ecb\u3059\u308b\u3002\u30c0\u30cb\u5e7c\u866b\u306f\u611f\u67d3\u3092\u53d7\u3051\u305f\u9f67\u6b6f\u985e\u3092\u5438\u8840\u3057\u3066\u611f\u67d3\u3057\u3001\u5909\u614b\u3057\u3066\u82e5\u866b\u3068\u306a\u308a\u3001\u539f\u866b\u3092\u4ed6\u306e\u52d5\u7269\u307e\u305f\u306f\u30d2\u30c8\u306b\u4f1d\u64ad\u3059\u308b\u3002\u8a73\u3057\u304f\u306fhttps:\/\/www.msdmanuals.com\/ja-jp\/%E3%83%97%E3%83%AD%E3%83%95%E3%82%A7%E3%83%83%E3%82%B7%E3%83%A7%E3%83%8A%E3%83%AB\/13-%E6%84%9F%E6%9F%93%E6%80%A7%E7%96%BE%E6%82%A3\/%E8%85%B8%E7%AE%A1%E5%A4%96%E5%AF%84%E7%94%9F%E5%8E%9F%E8%99%AB\/%E3%83%90%E3%83%99%E3%82%B7%E3%82%A2%E7%97%87 \u3092\u53c2\u7167\u306e\u3053\u3068\u3002\u3053\u306e\u539f\u866b\u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def \u306b\u304a\u3044\u3066\u306f\u3001NADPH2 \u306e\u751f\u7523\u306e\u307f\u306a\u3089\u305a\u3044\u308f\u3086\u308b\u89e3\u7cd6\u7cfb\u3068\u306e\u63a5\u7d9a\u3082\u5207\u308c\u3066\u3057\u307e\u3063\u3066\u304a\u308a\u3001\u7d4c\u8def\u3068\u3057\u3066\u306e\u4f53\u3092\u306a\u3057\u3066\u3044\u306a\u3044\u3002\u3053\u308c\u3092\u898b\u3066\u3069\u3046\u89e3\u91c8\u3059\u308c\u3070\u3044\u3044\u306e\u304b\u3001\u9014\u65b9\u306b\u66ae\u308c\u308b\u3057\u304b\u306a\u3044\u3002\u5bc4\u751f\u751f\u7269\u3067\u3042\u308b\u3068\u4e91\u3046\u30ed\u30b8\u30c3\u30af\u306b\u983c\u308b\u3057\u304b\u306a\u3055\u305d\u3046\u3060\u3002<\/p>\r\n\r\n\r\n\r\n<p>\u3000\u6b21\u306f<em>Babesia bigemina<\/em> \u306b\u3064\u3044\u3066\u3060\u304c\u3001\u725b\u3001\u6c34\u725b\u304a\u3088\u3073\u9e7f\u306b\u611f\u67d3\u3057\u3001\u4e2d\u5357\u7c73\u3001\u6771\u5357\u30a2\u30b8\u30a2\u3001\u30a2\u30d5\u30ea\u30ab\u3001\u8c6a\u5dde\u306b\u5206\u5e03\u3057\u3001\u30aa\u30a6\u30b7\u30de\u30c0\u30cb\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u30b3\u30a4\u30bf\u30de\u30c0\u30cb\u5c5e\u306e\u30de\u30c0\u30cb\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u308b\u3002\u3053\u308c\u307e\u305f\u8a73\u3057\u304f\u306fhttps:\/\/www.naro.affrc.go.jp\/org\/niah\/disease_fact\/k13.html\u3092\u53c2\u7167\u3057\u3066\u4e0b\u3055\u3044\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"708\" class=\"wp-image-8308\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-6-1024x708.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-6-1024x708.png 1024w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-6-300x207.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-6-768x531.png 768w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-6.png 1310w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\r\n<figcaption class=\"wp-element-caption\"><em>Babesia bigemina<\/em> \u306e\u6301\u3064\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def<\/figcaption>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u3000\u3053\u306e\u539f\u866b\u306b\u304a\u3044\u3066\u306f\u30006-phosphogluconolactonase\uff08EC 3.1.1.31\uff09\u3092\u6b20\u3044\u3066\u3044\u3066\u3001\u4e00\u898b\u4e8c\u3064\u306e\u7cfb\u304c\u7e4b\u304c\u3063\u3066\u3044\u306a\u3044\u3088\u3046\u306b\u898b\u3048\u308b\u306e\u3060\u304c\u3001\u3053\u306e\u9175\u7d20\u306f\u6b21\u306e\u53cd\u5fdc\u3092\u89e6\u5a92\u3059\u308b\u3002<\/p>\r\n\r\n\r\n<div class=\"wp-block-image\">\r\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"502\" height=\"179\" class=\"wp-image-8312\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-7.png\" alt=\"\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-7.png 502w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2023\/09\/image-7-300x107.png 300w\" sizes=\"auto, (max-width: 502px) 100vw, 502px\" \/><\/figure>\r\n<\/div>\r\n\r\n\r\n<p>\u3000\u90fd\u5408\u306e\u826f\u3044\u89e3\u91c8\u3070\u304b\u308a\u6301\u3061\u51fa\u3057\u3066\u6c17\u304c\u91cd\u3044\u306e\u3060\u304c\u3001\u3053\u308c\u306f\u5358\u306a\u308b\u5206\u5b50\u5185\u74b0\u5316\u53cd\u5fdc\u3067\u3042\u308a\u6c34\u4e2d\u3067\u3042\u3063\u3066\u3082\u9032\u307e\u306a\u3044\u308f\u3051\u3067\u306f\u306a\u3044\u3002\u4ed6\u306e\u53cd\u5fdc\u3067\u6a5f\u80fd\u3059\u308b\u57fa\u8cea\u7279\u7570\u6027\u306e\u4f4e\u3044\u8131\u6c34\u9175\u7d20\u304c\u3001\u3053\u306e\u6bb5\u968e\u3092\u62c5\u3063\u3066\u3044\u308b\u304b\u3082\u3057\u3066\u306a\u3044\u3057\u3001\u30db\u30b9\u30c8\u306e\u3082\u3064\u9175\u7d20\u3092\u501f\u7528\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u3082\u6368\u3066\u304d\u308c\u306a\u3044\u3002\u306a\u3069\u3068\u3044\u3046\u3067\u305f\u3089\u3081\u306b\u8fd1\u3044\u8a00\u3044\u8a33\u3067 NADPH2 \u751f\u5408\u6210\u306f\u53ef\u80fd\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306b\u3057\u3066\u304a\u3053\u3046\u3002\u8a00\u3046\u307e\u3067\u3082\u306a\u304f\u3001\u305d\u306e\u30b9\u30d4\u30fc\u30c9\u306f\u9ad8\u304f\u306f\u306a\u3044\u306b\u9055\u3044\u306a\u3044\u3002<em>Babesia bigemina<\/em> \u306b\u3064\u3044\u3066\u306e\u8a73\u3057\u3044\u60c5\u5831\u306f\u4e0b\u8a18\u3092\u53c2\u7167\u306e\u3053\u3068\u3002<\/p>\r\n\r\n\r\n\r\n<p><a href=\"https:\/\/www.rakuno.ac.jp\/wp-content\/themes\/rgu\/file\/reserch-report_1212.pdf\">https:\/\/www.rakuno.ac.jp\/wp-content\/themes\/rgu\/file\/reserch-report_1212.pdf<\/a><\/p>\r\n\r\n\r\n\r\n<p>\u3000\u4eca\u56de\u306f\u4f55\u3068\u306a\u304f\u81ea\u4fe1\u3092\u6301\u3066\u306a\u3044\u3002\u5171\u751f\u3068\u4e91\u3046\u73fe\u8c61\u306b\u983c\u308a\u3059\u304e\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u3067\u3082\u3053\u3053\u3092\u901a\u3089\u306a\u3044\u3068\u6b21\u306b\u3044\u3051\u306a\u3044\u6c17\u304c\u3057\u3066\u3044\u307e\u3059\u3002\u3068\u306b\u304b\u304f\u4e2d\u9593\u6bb5\u968e\u306b\u3042\u308b\u3068\u3044\u3046\u4e8b\u3067\u3059\u3002<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>\u3000\u6b21\u306f\u30c7\u30a3\u30b9\u30b3\u30bb\u30a2\u7db1(class Discosea)\u306b\u5c5e\u3059\u308b Acanthamo &hellip; <a href=\"https:\/\/bamboolab.yamasatoagr.com\/?p=8277\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[180,1],"tags":[],"class_list":["post-8277","post","type-post","status-publish","format-standard","hentry","category-180","category-1"],"_links":{"self":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/8277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8277"}],"version-history":[{"count":19,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/8277\/revisions"}],"predecessor-version":[{"id":8516,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/8277\/revisions\/8516"}],"wp:attachment":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}