{"id":5660,"date":"2017-04-15T13:36:04","date_gmt":"2017-04-15T04:36:04","guid":{"rendered":"http:\/\/bamlab.ok-japan.com\/?p=5660"},"modified":"2019-11-02T13:36:26","modified_gmt":"2019-11-02T04:36:26","slug":"%e9%81%8e%e5%89%b0%e3%81%a8%e8%95%a9%e5%b0%bd%e3%80%8033","status":"publish","type":"post","link":"https:\/\/bamboolab.yamasatoagr.com\/?p=5660","title":{"rendered":"\u904e\u5270\u3068\u8569\u5c3d\u300033"},"content":{"rendered":"\n<h4 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class=\"wp-block-heading\">\u3000\u3068\u306f\u3044\u3048\u3001\u4eca\u56de\u307e\u3067\u306f\u81ea\u91cd\u3057\u3066\u304a\u3068\u306a\u3057\u304f\u8a71\u3092\u9032\u3081\u308b\u3053\u3068\u306b\u3059\u308b\u3002 &nbsp;\u524d\u56de\u307e\u3067\u306b\u30c7\u30aa\u30ad\u30b7\u30a6\u30ea\u30b8\u30f3\u30c8\u30ea\u30ea\u30f3\u9178\uff08dUTP\uff09\u306e\u751f\u5408\u6210\u304c\u7d42\u308f\u3063\u3066\u3044\u305f\u3002\u4eca\u56de\u306fdUTP\u304b\u3089 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number\u3092\u793a\u3057\u3066\u3044\u308b\u306e\u3067\u3001\u8208\u5473\u306e\u3042\u308b\u65b9\u306f\u3069\u3093\u306a\u53cd\u5fdc\u3092\u89e6\u5a92\u3057\u3066\u3044\u308b\u304b\u691c\u7d22\u3055\u308c\u308b\u3053\u3068\u3092\u304a\u52e7\u3081\u3059\u308b\u3002\u73fe\u5728\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u308bdUMP\u304b\u3089dTMP\u3078\u306e\u5909\u63db\u306f2.1.1.48\u306b\u3088\u3063\u3066\u89e6\u5a92\u3055\u308c\u308b\u53cd\u5fdc\u3067\u3042\u308a\u3001N<sup>5<\/sup>, N<sup>10<\/sup>-Methylene-tetrahydrofolate\u304b\u30895,6,7,8-Tetrahydrofolate\u3078\u306e\u5909\u63db\u306b\u4f34\u3046\u53cd\u5fdc\u3067\u3042\u308b\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u3000\u5c11\u3057\u3060\u3051\u88dc\u8db3\u3059\u308b\u304c\u3001\u5730\u7403\u4e0a\u306e\u751f\u7269\u306b\u3068\u3063\u30661\u70ad\u7d20\u5316\u5408\u7269\u306e\u6271\u3044\u306f\u3044\u3055\u3055\u304b\u96e3\u3057\u305d\u3046\u3060\u3002\u30e1\u30bf\u30ce\u30fc\u30eb\u3068\u30a8\u30bf\u30ce\u30fc\u30eb\u3001\u30db\u30eb\u30e0\u30a2\u30eb\u30c7\u30d2\u30c9\u3068\u30a2\u30bb\u30c8\u30a2\u30eb\u30c7\u30d2\u30c9\u3001\u30ae\u9178\u3068\u9162\u9178\u306a\u3069\u3092\u8f03\u3079\u3066\u3082\u30011\u70ad\u7d20\u5316\u5408\u7269\u306e\u6bd2\u6027\u304c\u9ad8\u3044\u3002\u3053\u3046\u3057\u305f1\u70ad\u7d20\u5316\u5408\u7269\u7fa4\u3092\u5229\u7528\u3059\u308b\u305f\u3081\u306e\u30b7\u30b9\u30c6\u30e0\u306f\u8449\u9178\u985e\u3092\u88dc\u9175\u7d20\u3068\u3059\u308b\u9175\u7d20\u7fa4\u304c\u50cd\u3044\u3066\u3044\u308b\u3002\u3053\u3046\u66f8\u304f\u3068\u6bd2\u6027\u306e\u3042\u308b1\u70ad\u7d20\u5316\u5408\u7269\u306e\u89e3\u6bd2\u3092\u62c5\u3046\u3088\u3046\u306b\u8aa4\u89e3\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308b\u304c\u3001\u5b9f\u969b\u306f\u305d\u3046\u3067\u306f\u306a\u304f\u3082\u3063\u3068\u7a4d\u6975\u7684\u306a\u610f\u7fa9\u3092\u6301\u3064\u3002\u5148\u307b\u3069\u66f8\u3044\u305f\u304cDNA\u3092\u69cb\u6210\u3057\u3066\u3044\u308b\u30c1\u30df\u30f3\u6b8b\u57fa\u306e\u751f\u5408\u6210\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u30a2\u30c7\u30cb\u30f3\u3068\u30b0\u30a2\u30cb\u30f3\u306e\u751f\u5408\u6210\u306b\u304a\u3044\u3066\u3082\u5fc5\u9808\u3067\u3042\u308b\u3002\u3055\u3089\u306b\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u751f\u5408\u6210\u306e\u958b\u59cb\u30b3\u30c9\u30f3\u306b\u5bfe\u5fdc\u3059\u308bN-\u30db\u30eb\u30df\u30eb\u30e1\u30c1\u30aa\u30cb\u30f3\u306e\u30db\u30eb\u30df\u30eb\u57fa\u306e\u7d66\u6e90\u3082N<sup>10<\/sup>-Formyl-tetrahydrofolate\u3067\u3042\u308b\u3057\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u69cb\u6210\u3057\u3066\u3044\u308b\u30a2\u30df\u30ce\u9178\u306e\u4e2d\u3067\u3001\u30e1\u30c1\u30aa\u30cb\u30f3\u306e\u751f\u5408\u6210\u3001\u30b0\u30ea\u30b7\u30f3\u3068\u30bb\u30ea\u30f3\u306e\u76f8\u4e92\u5909\u63db\u306b\u3082\u5fc5\u9808\u3067\u3042\u308b\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">&nbsp; &nbsp;\u3053\u308c\u3089\u306e\u4e8b\u5b9f\u306f\u3001\u751f\u7269\u306e\u8d77\u6e90\u306b\u3064\u3044\u3066DNA\u30ef\u30fc\u30eb\u30c9\u4eee\u8aac\u30fbRNA\u30ef\u30fc\u30eb\u30c9\u4eee\u8aac\u30fb\u30d7\u30ed\u30c6\u30a4\u30f3\u30ef\u30fc\u30eb\u30c9\u4eee\u8aac\u306e\u3044\u305a\u308c\u3092\u53d6\u308b\u306b\u3057\u3066\u3082\u3001\u305d\u306e\u30ef\u30fc\u30eb\u30c9\u304c\u3067\u304d\u308b\u4ee5\u524d\u306b\u8449\u9178\u306e\u95a2\u4e0e\u3059\u308b\u4ee3\u8b1d\u7cfb\u304c\u6210\u7acb\u3057\u3066\u3044\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3066\u3044\u3044\u3060\u308d\u3046\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u3000\u305d\u3053\u3067dUMP\u304b\u3089dTMP\u3078\u306e\u5909\u63db\u53cd\u5fdc\u3067\u3042\u308b\u3002N<sup>5<\/sup>, N<sup>10<\/sup>-Methylene-tetrahydrofolate\u3092\u30e1\u30c1\u30eb\u57fa\u306e\u7d66\u6e90\u3068\u3057\u3066\u5229\u7528\u3059\u308b\u9175\u7d205,10-methylenetetrahydrofolate,NADPH:dUMP C-methyltransferase\u306b\u3088\u3063\u3066\u89e6\u5a92\u3055\u308c\u308b\u53cd\u5fdc\u3067\u3042\u308b\u3002\u53cd\u5fdc\u306f\u30ab\u30eb\u30dc\u30cb\u30eb\u57fa\u306e\u7acb\u3061\u4e0a\u304c\u308a\u3068\u5354\u594f\u3057\u3066\u9175\u7d20\u306e\u30b7\u30b9\u30c6\u30a4\u30f3\u6b8b\u57fa\u304c\u4ed8\u52a0\u3059\u308b\u3068\u3053\u308d\u304b\u3089\u306f\u3058\u307e\u308b\u3002\u751f\u6210\u3057\u305f\u30a8\u30ce\u30fc\u30eb\u4f53\u304c\u518d\u3073\u30b1\u30c8\u4f53\u306b\u623b\u308b\u3068\u304d\u3001N<sup>5<\/sup>, N<sup>10<\/sup>-Methylene-tetrahydrofolate\u304b\u3089\u751f\u6210\u3057\u305f10\u4f4d\u306e\u7a92\u7d20\u4e0a\u306b\u751f\u6210\u3057\u305f\u30a4\u30df\u30cb\u30a6\u30e0\u30a4\u30aa\u30f3\u306e\u70ad\u7d20\u539f\u5b50\u306b\u6c42\u6838\u7684\u306b\u4ed8\u52a0\u3092\u3059\u308b\u3002\u30e1\u30c1\u30ec\u30f3\u57fa\u3068\u30ab\u30eb\u30dc\u30cb\u30eb\u57fa\u306b\u631f\u307e\u308c\u305f\u30e1\u30c1\u57fa\u306e\u30d7\u30ed\u30c8\u30f3\u304c\u3001\u9175\u7d20\u5185\u306e\u5869\u57fa\u306b\u3088\u3063\u3066\u5f15\u304d\u629c\u304b\u308c\u3066\u30e1\u30c1\u30ec\u30f3\u57fa\u3092\u5f62\u6210\u3059\u308b\u3002\u3053\u306e\u30e1\u30c1\u30ec\u30f3\u57fa\u306b\u3001\u8449\u9178\u6b8b\u57fa\u306e6\u4f4d\u4f3c\u5408\u3063\u305f\u6c34\u7d20\u304c\u30cf\u30a4\u30c9\u30e9\u30a4\u30c9\u3068\u3057\u3066\u4ed8\u52a0\u3059\u308b\u3068\u540c\u6642\u306b\u9175\u7d20\u304c\u5143\u306b\u623b\u308b\u3068\u3044\u3046\u53cd\u5fdc\u306b\u3088\u308a\u3081\u3067\u305f\u304fdTMP\u304c\u3064\u304f\u3089\u308c\u308b\u8a33\u3067\u3042\u308b\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u3000\u3053\u308c\u306b\u7d9a\u304f2\u6bb5\u968e\u306e\u30ea\u30f3\u9178\u5316\u53cd\u5fdc\u306f\u3001\u306a\u3093\u3067\u3082\u306a\u3044ATP\u30ea\u30f3\u9178\u57fa\u306e\u8ee2\u79fb\u3067\u3042\u308a\u3055\u307b\u3069\u306e\u8aac\u660e\u306f\u3044\u3089\u306a\u3044\u3060\u308d\u3046\u3002\u56f3\u3060\u3051\u3092\u793a\u3057\u3066\u304a\u304f\u3053\u3068\u306b\u3059\u308b\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\"><a href=\"http:\/\/bamboolab.ok-japan.com\/?attachment_id=4094\"><\/a><\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u3088\u3046\u3084\u304f\u30d4\u30ea\u30df\u30b8\u30f3\u5869\u57fa\u306e\u751f\u5408\u6210\u304c\u7d42\u308f\u3063\u305f\u304c\u3001\u3055\u3066\u4f55\u306e\u305f\u3081\u306b\u6838\u9178\u306e\u751f\u5408\u6210\u3092\u8ff0\u3079\u308b\u7fbd\u76ee\u306b\u306a\u3063\u305f\u306e\u304b\u3002\u3064\u3044\u5148\u307b\u3069\u307e\u3067\u306f\u3001\u30dd\u30eb\u30d5\u30a3\u30ea\u30f3\u306e\u8a71\u3092\u3057\u3066\u3044\u305f\u306f\u305a\u3067\u3042\u308b\u3002\u6b21\u56de\u306e\u30a2\u30c3\u30d7\u307e\u3067\u306b\u3001\u4f55\u3092\u554f\u984c\u306b\u3057\u3066\u3044\u305f\u306e\u304b\u601d\u3044\u51fa\u3057\u3066\u3044\u305f\u3060\u3051\u308c\u3070\u5e78\u751a\u3067\u3042\u308b\u3002<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u904e\u5270\u3068\u8569\u5c3d\u300034\u3000\u306b\u7d9a\u304f<\/h4>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp;\u3000\u4eca\u56de\u3067\u30d4\u30ea\u30df\u30b8\u30f3\u5869\u57fa\u306e\u751f\u5408\u6210\u306f\u7d42\u308f\u308b\u3002\u3053\u3053\u307e\u3067\u306f\u3001\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044 &hellip; <a href=\"https:\/\/bamboolab.yamasatoagr.com\/?p=5660\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5660","post","type-post","status-publish","format-standard","hentry","category-1"],"_links":{"self":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5660"}],"version-history":[{"count":1,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5660\/revisions"}],"predecessor-version":[{"id":5661,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5660\/revisions\/5661"}],"wp:attachment":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}