{"id":5458,"date":"2015-01-09T15:33:07","date_gmt":"2015-01-09T06:33:07","guid":{"rendered":"http:\/\/bamlab.ok-japan.com\/?p=5458"},"modified":"2019-11-01T15:33:29","modified_gmt":"2019-11-01T06:33:29","slug":"%e6%ad%b4%e5%8f%b2%e7%94%9f%e7%89%a9%e5%ad%a6%e3%83%bb%e3%83%bb%e3%83%bb%e4%b8%80%e6%ac%a1%e4%bb%a3%e8%ac%9d%e3%81%a8%e4%ba%8c%e6%ac%a1%e4%bb%a3%e8%ac%9d%e3%80%809","status":"publish","type":"post","link":"https:\/\/bamboolab.yamasatoagr.com\/?p=5458","title":{"rendered":"\u6b74\u53f2\u751f\u7269\u5b66\u30fb\u30fb\u30fb\u4e00\u6b21\u4ee3\u8b1d\u3068\u4e8c\u6b21\u4ee3\u8b1d\u30009"},"content":{"rendered":"\n

\u3000\u3000\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u3068\u3044\u3046\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3055\u308c\u3066\u3044\u308b\u4e00\u898b\u8907\u96d1\u306b\u898b\u3048\u308b\u30e2\u30eb\u30d2\u30cd\u3060\u304c\u3001\u3053\u306e\u5316\u5408\u7269\u306f2\u5206\u5b50\u306e\u30c1\u30ed\u30b7\u30f3\u304b\u3089\u751f\u5408\u6210\u3055\u308c\u308b\u3002\u30c1\u30ed\u30b7\u30f3\u304b\u3089\u30e2\u30eb\u30d2\u30cd\u307e\u3067\u306e\u751f\u5408\u6210\u3092(R)-Reticuline\u307e\u3067\u306e\u7cfb\u8def\u3068\u3001(R)-Reticuline\u304b\u3089\u30e2\u30eb\u30d2\u30cd\u307e\u3067\u306b\u5206\u3051\u3066\u8a18\u8ff0\u3057\u305f\u3044\u3002\u4f55\u6545(R)-Reticuline\u3067\u533a\u5207\u308b\u306e\u304b\uff1f\u4ed6\u610f\u306f\u306a\u3044\u3002ChemDraw\u306e\u56f31\u679a\u3067\u306f\u63cf\u304d\u304d\u308c\u306a\u3044\u304b\u3089\u306b\u904e\u304e\u306a\u3044\u3002\u5404\u6bb5\u968e\u306b\u8a18\u8f09\u3057\u3066\u3044\u308b\u6570\u5b57\u306f\u3001\u3044\u3064\u3082\u306e\u901a\u308aEC\u30ca\u30f3\u30d0\u30fc\u3067\u3042\u308b\u3002<\/p>\n\n\n\n

\u3000\u3000\u307e\u305a\u3001\u56f36-3\u304b\u3089\u59cb\u3081\u3088\u3046\u3002\u30e2\u30eb\u30d2\u30cd\u306e\u751f\u5408\u6210\u306b\u65bc\u3044\u3066\u306f\u30011\u5206\u5b50\u306e\u30c1\u30ed\u30b7\u30f3\u304c\u30aa\u30ad\u30b7\u30b2\u30ca\u30fc\u30bc\u306e\u4f5c\u7528\u3067\u6c34\u9178\u5316\u3092\u53d7\u3051\u305f\u3042\u3068\u8131\u70ad\u9178\u3092\u53d7\u3051\u3066\u30c9\u30fc\u30d1\u30df\u30f3\u304c\u751f\u6210\u3059\u308b\u3002\u3082\u30461\u5206\u5b50\u306e\u30c1\u30ed\u30b7\u30f3\u306f\u9178\u5316\u7684\u306b\u8131\u30a2\u30df\u30ce\u3092\u8d77\u3053\u3057\u30664-\u30d2\u30c9\u30ed\u30ad\u30b7\u30d5\u30a7\u30cb\u30eb\u30d4\u30eb\u30d3\u30f3\u9178\u3068\u306a\u3063\u305f\u5f8c\u30014-\u30d2\u30c9\u30ed\u30ad\u30b7\u30d5\u30a7\u30cb\u30eb\u30d4\u30eb\u30d3\u30f3\u9178\u30c7\u30ab\u30eb\u30dc\u30ad\u30b7\u30e9\u30fc\u30bc\u306e\u89e6\u5a92\u4e0b\u306b4-\u30d2\u30c9\u30ed\u30ad\u30b7\u30d5\u30a7\u30cb\u30eb\u30a2\u30bb\u30c8\u30a2\u30eb\u30c7\u30d2\u30c9\u3068\u306a\u308b\u3002\u3053\u306e\u30a2\u30eb\u30c7\u30d2\u30c9\u304c\u5148\u306b\u751f\u6210\u3057\u305f\u30c9\u30fc\u30d1\u30df\u30f3\u3068\u306e\u9593\u3067\u8131\u6c34\u7e2e\u5408\u3092\u8d77\u3053\u3057\u3066\u30b7\u30c3\u30d5\u5869\u57fa\u3068\u306a\u3063\u305f\u5f8c\u3001\u3059\u3050\u306b\u30ad\u30ce\u30ea\u30f3\u74b0\u3092\u5f62\u6210\u3057\u3066 (S)-Norcoclaurine\u3068\u306a\u308b\u3002(S)-Norcoclaurine\u306b\u5b58\u5728\u3059\u308b\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u74b0\u306e2\u4f4d\u306e\u7a92\u7d20\u539f\u5b50\u30686\u4f4d\u306e\u6c34\u9178\u57fa\u304c\u30e1\u30c1\u30eb\u57fa\u8ee2\u4f4d\u3092\u53d7\u3051\u3066(S)-N-Methylcoclaurine\u3068\u306a\u3063\u305f\u5f8c\u3001\u3082\u3046\u4e00\u3064\u306e\u82b3\u9999\u74b0\u306e3\u2019\u4f4d\u304c\u30e2\u30ce\u30aa\u30ad\u30b7\u30b2\u30ca\u30fc\u30bc\u306b\u3088\u308b\u6c34\u9178\u5316\u3092\u53d7\u3051\u30663′-Hydroxy-N-methyl-(S)-coclaurine\u3078\u30013′-Hydroxy-N-methyl-(S)-coclaurine\u306e4\u2019\u4f4d\u306e\u6c34\u9178\u57fa\u304c\u30e1\u30c1\u30eb\u5316\u3092\u53d7\u3051\u3066(S)-Reticuline\u3092\u4e0e\u3048\u308b\u3002<\/p>\n\n\n\n

\"\u56f36-3\u3000\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u30001<\/a>
\u56f36-3\u3000\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u30001<\/figcaption><\/figure><\/div>\n\n\n\n

\u3000\u3000\u3053\u306e\u8fba\u308a\u306e\u9178\u5316\u53cd\u5fdc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u30ea\u30b0\u30cb\u30f3\u751f\u5408\u6210\u306e8\u8fba\u308a\u306b\u66f8\u3044\u305f\u3082\u306e\u3068\u540c\u69d8\u3067\u3042\u308d\u3046\u3002\u30e2\u30eb\u30d2\u30cd\u3078\u5411\u304b\u3046\u53cd\u5fdc\u7cfb\u306f\u3001(S)-Reticuline\u304b\u3089(R)-Reticuline\u3078\u3068\u5909\u63db\u3055\u308c\u305f\u5f8c\u9032\u3093\u3067\u3044\u304f\u306e\u3060\u304c\u3001\u3053\u306e\u4e00\u5bfe\u306e\u5149\u5b66\u7570\u6027\u4f53\u9593\u306e\u5909\u63db\u53cd\u5fdc\u306f\u3044\u304f\u3076\u3093\u4e0d\u53ef\u89e3\u3067\u3042\u308b\u3002\u56f36-3\u306b\u793a\u3057\u305f\u4e0b\u5074\u306e\u7cfb\u3092\u901a\u308b\u306e\u3067\u3042\u308c\u3070\u4e00\u65e6\u9178\u5316\u3057\u3066\u4e0d\u6574\u70ad\u7d20\u3092\u6d88\u3057\u305f\u5f8c\u3001\u7acb\u4f53\u7279\u7570\u6027\u3092\u6301\u3064\u9084\u5143\u9175\u7d201.5.1.27\u306e\u4f5c\u7528\u3067(R)-Reticuline\u3092\u751f\u5408\u6210\u3059\u308b\u3068\u8aac\u660e\u3067\u304d\u308b\u306e\u3060\u304c\u3001Laudanine\u306e\u5b58\u5728\u304c\u3069\u3046\u3082\u6c17\u306b\u306a\u308b\u306e\u3067\u3042\u308b\u3002\u9175\u7d202.1.1.291\u306e\u53cd\u5fdc\u306e\u65b9\u5411\u304c(R)-Reticuline\u304b\u3089\u3082(S)-Reticuline\u304b\u3089\u3082Laudanine\u751f\u6210\u306e\u65b9\u5411\u306b\u5411\u304b\u3063\u3066\u3044\u308b\u306e\u3067\u3042\u308b\u3002\u3053\u306e\u70b9\u306b\u3064\u3044\u3066\u306f\u3001\u5e73\u8861\u5b9a\u6570\u304cLaudanine\u5074\u306b\u5bc4\u3063\u3066\u3044\u308b\u3068\u4e91\u3046\u3053\u3068\u3067\u3001\u53cd\u5fdc\u81ea\u4f53\u306f\u53ef\u9006\u53cd\u5fdc\u3067\u3042\u308b\u3068\u7406\u89e3\u3057\u3066\u304a\u304f\u3053\u3068\u306b\u3059\u308b\u3002\u305d\u308c\u306b\u3057\u3066\u30827\u4f4d\u306e\u6c34\u9178\u57fa\u306e\u30e1\u30c1\u30eb\u5316\u3042\u308b\u3044\u306f\u8131\u30e1\u30c1\u30eb\u5316\u306b\u4f34\u3044\u3001\u3069\u306e\u3088\u3046\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u30671\u4f4d\u306e\u30e9\u30bb\u30df\u5316\u304c\u8d77\u3053\u308b\u306e\u304b\u3001\u79c1\u81ea\u8eab\u304c\u7406\u89e3\u3067\u304d\u3066\u3044\u306a\u3044\u3002<\/p>\n\n\n\n

\u3000\u3000\u56f36-4\u306f(S)-Reticuline\u307e\u3067\u306e\u3082\u3046\u3072\u3068\u3064\u306e\u751f\u5408\u6210\u3092\u793a\u3057\u3066\u3044\u308b\uff61\u3053\u306e\u7cfb\u306f\u56f36-3\u306e\u7cfb\u3068\u6df7\u5728\u3057\u3066\u52d5\u3044\u3066\u3044\u308b\u7cfb\u3067\u3042\u308d\u3046\u3002\u50cd\u3044\u3066\u3044\u308b\u9175\u7d20\u306b\u3082\u5171\u901a\u306a\u7269\u304c\u3042\u308b\u3002\u3057\u304b\u3057\u3001\u6df7\u3056\u3063\u305f\u72b6\u6cc1\u3067\u8a18\u8ff0\u3059\u308b\u3068\u5206\u304b\u308a\u306b\u304f\u304f\u306a\u308b\u306e\u3067\u3001\u307e\u305a\u72ec\u7acb\u3057\u3066\u52d5\u3044\u3066\u3044\u308b\u3068\u3044\u3046\u7acb\u5834\u304b\u3089\u8ff0\u3079\u308b\u3053\u3068\u306b\u3059\u308b\u3002<\/p>\n\n\n\n

\"\u56f36-4\u3000\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u30002<\/a>
\u56f36-4\u3000\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u30002<\/figcaption><\/figure><\/div>\n\n\n\n

\u3000\u3000\u3053\u306e\u5834\u5408\u30822\u5206\u5b50\u306e\u30c1\u30ed\u30b7\u30f3\u304b\u3089\u59cb\u3081\u3088\u3046\u3002\u307e\u305a2\u5206\u5b50\u306e\u30c1\u30ed\u30b7\u30f3\u304c\u8131\u70ad\u9178\u53cd\u5fdc\u3092\u53d7\u3051\u3066\u30012\u5206\u5b50\u306e\u30c1\u30e9\u30df\u30f3\u304c\u751f\u3058\u308b\u3002\u3053\u306e\u30c1\u30e9\u30df\u30f3\u304cmonophenol oxidase\u306b\u3088\u308b\u6c34\u9178\u5316\u3092\u53d7\u3051\u30662\u5206\u5b50\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u306b\u5909\u63db\u3055\u308c\u308b\u3002\u52ff\u8ad6\u3001\u3053\u306e\u7cfb\u306b\u306fL-DOPA\u3092\u901a\u308b\u7cfb\u3082\u5b58\u5728\u3059\u308b\u3002\u751f\u6210\u3057\u305f\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u3046\u30611\u5206\u5b50\u306faromatic amine dehydrogenase\u3042\u308b\u3044\u306famine oxidase \u3068\u547c\u3070\u308c\u308b\u9178\u5316\u9175\u7d20\u306e\u4f5c\u7528\u306b\u3088\u308a3,4-Dihydroxyphenylacetaldehyde\u3078\u3068\u9178\u5316\u3055\u308c\u308b\u3002\u3053\u306e\u6642\u767a\u751f\u3059\u308b\u30a2\u30f3\u30e2\u30cb\u30a2\u306f\u518d\u5229\u7528\u3055\u308c\u308b\u306e\u3067\u3042\u308d\u3046\u3002\u751f\u6210\u3057\u305f3,4-Dihydroxyphenylacetaldehyde\u306f\u3082\u30461\u5206\u5b50\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u3068\u8131\u6c34\u7e2e\u5408\u3057\u3066\u30b7\u30c3\u30d5\u5869\u57fa\u3092\u5f62\u6210\u3057\u305f\u5f8c\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u9593\u3092\u5f62\u6210\u3057\u3066(S)-Norlaudanosoline\u3092\u4e0e\u3048\u308b\u3002\u3053\u306e\u5f8c\u30013\u6bb5\u968e\u306b\u6e21\u308b\u30e1\u30c1\u30eb\u57fa\u8ee2\u79fb\u306b\u3088\u3063\u3066(S)-Reticuline\u306b\u5909\u63db\u3055\u308c\u3001\u56f36-3\u306e\u7cfb\u306b\u5408\u6d41\u3059\u308b\u308f\u3051\u3067\u3042\u308b\u3002\u91cf\u7684\u306a\u554f\u984c\u306f\u4f59\u308a\u306b\u8907\u96d1\u3059\u304e\u3066\u3053\u3053\u3067\u306f\u8003\u616e\u3057\u306a\u3044\u3053\u3068\u306b\u3059\u308b\u3002<\/p>\n\n\n\n

\u3000\u3000\u56f36-5\u306b\u79fb\u308b\u3002Salutaridine synthase\u3068\u547c\u3070\u308c\u308bP450\u306b\u5206\u985e\u3055\u308c\u308b\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\u304c\u30012\u3064\u306e\u30d9\u30f3\u30bc\u30f3\u74b0\u3067C-C\u30d5\u30a7\u30ce\u30fc\u30eb\u30ab\u30c3\u30d7\u30ea\u30f3\u30b0\u3068\u547c\u3070\u308c\u308b\u7d50\u5408\u304c\u8d77\u3053\u308aSalutaridine\u304c\u751f\u6210\u3059\u308b\u3002\u3053\u306e\u53cd\u5fdc\u306b\u3064\u3044\u3066\u306f\u3001\u5f8c\u3067\u5c11\u3057\u88dc\u8db3\u3059\u308b\u304b\u3082\u77e5\u308c\u306a\u3044\u3002\u6b21\u304e\u306bSalutaridine\u306e\u30ab\u30eb\u30dc\u30cb\u30eb\u57fa\u304c\u7acb\u4f53\u9078\u629e\u7684\u306b\u9084\u5143\u3055\u308c\u3066Salutaridinol\u3001\u751f\u6210\u3057\u305fSalutaridinol\u306e\u6c34\u9178\u57fa\u304cAcetylCoA\u306b\u3088\u308b\u30a2\u30bb\u30c1\u30eb\u5316\u3092\u53d7\u3051\u30667-O-Acetylsalutaridinol\u306b\u306a\u308b\u3068\u3001\u30d5\u30a7\u30ce\u30fc\u30eb\u6027\u6c34\u9178\u57fa\u306b\u3088\u308b\u653b\u6483\u3068\u540c\u6642\u306b\u30a2\u30bb\u30c8\u30ad\u30b7\u30eb\u57fa\u304c\u8131\u96e2\u3059\u308b\u53cd\u5fdc\u304c\u9175\u7d20\u306e\u5b58\u5728\u306a\u3057\u306b\u9032\u884c\u3057\u3066Thebaine\u304c\u751f\u6210\u3059\u308b\u3002<\/p>\n\n\n\n

\"Fig.<\/a>
Fig. 6-5 \u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u30003<\/figcaption><\/figure><\/div>\n\n\n\n

\u3000\u3000\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u306b\u65bc\u3044\u3066\u306f\u3001\u30e1\u30c8\u30ad\u30b7\u57fa\u3092\u9178\u5316\u7684\u306b\u6c34\u9178\u57fa\u306b\u5909\u66f4\u3057\u306a\u304c\u3089\u53cd\u5fdc\u3092\u9032\u3081\u308b\u898b\u6163\u308c\u306a\u3044\u9175\u7d20\u304c\u91cd\u8981\u306a\u5f79\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u5834\u9762\u304c\u3042\u308b\u304c\u3001Thebaine\u304b\u3089Neopinone\u3078\u306e\u5909\u63db\u306f\u305d\u306e\u4f8b\u3067\u3042\u308b\u3002\u591a\u5206\u3060\u304c\u3001\u30e1\u30c1\u30eb\u57fa\u304c\u6c34\u9178\u5316\u3092\u53d7\u3051\u751f\u6210\u3057\u305f\u30d8\u30df\u30a2\u30bb\u30bf\u30fc\u30eb\u304c\u30db\u30eb\u30e0\u30a2\u30eb\u30c7\u30d2\u30c9\u3068\u30a8\u30ce\u30fc\u30eb\u3078\u3068\u5909\u63db\u3055\u308c\u308b\u53cd\u5fdc\u3067\u3042\u308d\u3046\u3002\u3053\u3046\u3057\u3066\u5f97\u3089\u308c\u308bNeopinone\u306f\u3088\u308a\u5b89\u5b9a\u306aab\u4e0d\u98fd\u548c\u30b1\u30c8\u30f3\u3078\u3068\u81ea\u52d5\u7684\u306b\u5909\u5316\u3057Codeinone\u3068\u306a\u308b\u3002\u5f8c\u306f\u7c21\u5358\u3067\u3042\u308b\u3002Codeinone\u306f\u7acb\u4f53\u9078\u629e\u7684\u306bre\u9762\u304b\u3089\u306e\u30d2\u30c9\u30ea\u30c9\u9084\u5143\u306b\u3088\u308aCodeine\u306b\u3001Codeine\u306b\u6b8b\u3063\u3066\u3044\u308b\u3082\u3046\u4e00\u3064\u306e\u30e1\u30c8\u30ad\u30b7\u57fa\u304c\u3084\u306f\u308a\u9178\u5316\u7684\u306b\u6c34\u9178\u57fa\u3078\u3068\u5909\u63db\u3055\u308c\u3066Morphine\u304c\u5b8c\u6210\u3059\u308b\u3002<\/p>\n\n\n\n

\u3000\u3000Thebaine\u3092\u57fa\u70b9\u3068\u3059\u308b\u3082\u3046\u4e00\u3064\u306e\u751f\u5408\u6210\u7cfb\u306f\u3001\u53cd\u5fdc\u306e\u9806\u5e8f\u304c\u5165\u308c\u4ee3\u308f\u3063\u305f\u7cfb\u3068\u898b\u308c\u3070\u3088\u3044\u3002Thebaine\u306e4\u2019\u4f4d\u306b\u7531\u6765\u3059\u308b\u30e1\u30c8\u30ad\u30b7\u57fa\u304c\u5148\u306b\u9178\u5316\u7684\u306b\u6c34\u9178\u57fa\u3078\u3068\u5909\u63db\u3055\u308c\u3066Oripavine\u3068\u306a\u3063\u305f\u5f8c\u30016\u4f4d\u306e\u30e1\u30c8\u30ad\u30b7\u57fa\u304c\u540c\u3058\u304f\u9178\u5316\u3055\u308c\u3066Morphinone\u3068\u306a\u308a\u3001\u7d9a\u3044\u3066\u7acb\u4f53\u9078\u629e\u7684\u306bre\u9762\u304b\u3089\u306e\u30d2\u30c9\u30ea\u30c9\u9084\u5143\u304c\u8d77\u3053\u308aMorphine\u304c\u5b8c\u6210\u3059\u308b\u3002<\/p>\n\n\n\n

\u3055\u3066\u3001\u3053\u308c\u30893\u679a\u306e\u56f3\u3092\u9023\u7d9a\u3057\u3066\u4e26\u3079\u3066\u4e0a\u8a18\u306e\u8aac\u660e\u3092\u4ed8\u3051\u308c\u3070\u3001\u521d\u5b66\u8005\u3092\u300c\u3053\u308c\u304c\u30e2\u30eb\u30d2\u30cd\u306e\u751f\u5408\u6210\u7cfb\u3060\u300d\u3068\u7d0d\u5f97\u3055\u305b\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u3053\u3068\u3067\u306f\u306a\u3044\u3002\u4f3c\u305f\u3053\u3068\u3092\u79c1\u3082\u3084\u3063\u3066\u304d\u305f\u3002\u300c\u3060\u304c\u300d\u3067\u3042\u308b\u3001\u56f36-7\u3092\u898b\u3066\u3001\u30e2\u30eb\u30d2\u30cd\u306e\u751f\u5408\u6210\u7cfb\u306f\u3068\u3044\u3046\u8b70\u8ad6\u3092\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u304b\u3002\u56f36-7\u306f\u30e2\u30eb\u30d2\u30cd\u3092\u542b\u3080\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u306e\u751f\u5408\u6210\u7cfb\u3092\u793a\u3057\u3066\u3044\u308b\u304c\u3001\u5de6\u5074\u306e\u7e26\u306b\u964d\u308a\u3066\u30e2\u30eb\u30d2\u30cd\u306b\u9023\u306a\u308b\u90e8\u5206\u306e\u307f\u3092\u6063\u610f\u7684\u306b\u5207\u308a\u51fa\u3057\u3066\u30e2\u30eb\u30d2\u30cd\u751f\u5408\u6210\u7cfb\u3068\u3057\u3066\u63cf\u3044\u305f\u308f\u3051\u3067\u3042\u308b\u3002<\/p>\n\n\n\n

\"\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8\uff082015-01-07<\/a>
\u56f36-7\u3000\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u306e\u751f\u5408\u6210\u7cfb\uff08KEGG\u3088\u308a\u5f15\u7528\uff09<\/figcaption><\/figure><\/div>\n\n\n\n

\u3000\u3000\u3055\u3089\u306b\u56f36-8\u3092\u307f\u308c\u3070\u3001\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u751f\u5408\u6210\u3055\u3048\u3082\u3001\u30c1\u30ed\u30b7\u30f3\u4ee3\u8b1d\u306e\u307b\u3093\u306e\u4e00\u90e8\u5206\u306b\u904e\u304e\u306a\u3044\u3053\u3068\u306f\u660e\u767d\u3067\u3042\u308b\u3002\u8981\u3059\u308b\u306b\u3001\u30e2\u30eb\u30d2\u30cd\u3068\u3044\u30461\u3064\u306e\u4ee3\u8b1d\u7269\u304c\u3001\u30d2\u30c8\u306b\u5bfe\u3057\u3066\u7279\u7570\u7684\u306a\u6d3b\u6027\u3092\u6301\u3061\u85ac\u5b66\u3068\u3044\u3046\u5206\u91ce\u3067\u5927\u304d\u306a\u8208\u5473\u3092\u3082\u305f\u308c\u305f\u304c\u6545\u306b\u63cf\u304b\u308c\u308b\u7cfb\u306b\u904e\u304e\u306a\u3044\u3002\u30e2\u30eb\u30d2\u30cd\u3082\u307e\u305f\u3001\u4e8c\u9178\u5316\u70ad\u7d20\u304b\u3089\u7cd6\u3078\u3001\u7cd6\u304b\u3089\u30a2\u30df\u30ce\u9178\u3078\u3068\u5909\u63db\u3055\u308c\u3066\u5f79\u5272\u3092\u679c\u305f\u3057\u518d\u5ea6\u4e8c\u9178\u5316\u70ad\u7d20\u3068\u30a2\u30f3\u30e2\u30cb\u30a2\u3078\u623b\u3063\u3066\u3044\u304f\u904e\u7a0b\u306b\u5b58\u5728\u3059\u308b\u4e00\u3064\u306e\u5fae\u91cf\u7269\u8cea\u306b\u904e\u304e\u306a\u3044\u306e\u3067\u3042\u308b\u3002<\/p>\n\n\n\n

\"\u56f36-7\u3000\u30c1\u30ed\u30b7\u30f3\u4ee3\u8b1d\u7cfb\"<\/a>
\u56f36-8\u3000\u30c1\u30ed\u30b7\u30f3\u4ee3\u8b1d\u7cfb\uff08KEGG\u3088\u308a\u5f15\u7528\uff09<\/figcaption><\/figure><\/div>\n\n\n\n

\u6b74\u53f2\u751f\u7269\u5b66\u30fb\u30fb\u30fb\u4e00\u6b21\u4ee3\u8b1d\u3068\u4e8c\u6b21\u4ee3\u8b1d\u300010\u3000\u306b\u7d9a\u304f<\/p>\n","protected":false},"excerpt":{"rendered":"

\u3000\u3000\u30a4\u30bd\u30ad\u30ce\u30ea\u30f3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u3068\u3044\u3046\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3055\u308c\u3066\u3044\u308b\u4e00\u898b\u8907\u96d1\u306b\u898b\u3048\u308b\u30e2\u30eb\u30d2 … \u7d9a\u304d\u3092\u8aad\u3080 →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5458","post","type-post","status-publish","format-standard","hentry","category-1"],"_links":{"self":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5458","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5458"}],"version-history":[{"count":1,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5458\/revisions"}],"predecessor-version":[{"id":5459,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=\/wp\/v2\/posts\/5458\/revisions\/5459"}],"wp:attachment":[{"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5458"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5458"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bamboolab.yamasatoagr.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5458"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}