{"id":5303,"date":"2023-01-23T02:29:00","date_gmt":"2023-01-22T17:29:00","guid":{"rendered":"http:\/\/bamlab.ok-japan.com\/?p=5303"},"modified":"2023-01-23T02:30:37","modified_gmt":"2023-01-22T17:30:37","slug":"%e6%ad%b4%e5%8f%b2%e7%94%9f%e7%89%a9%e5%ad%a6%e3%80%80tca%e5%9b%9e%e8%b7%af%e3%81%b8%e3%81%ae%e7%95%b0%e8%ab%96-8","status":"publish","type":"post","link":"https:\/\/bamboolab.yamasatoagr.com\/?p=5303","title":{"rendered":"\u6b74\u53f2\u751f\u7269\u5b66\u3000TCA\u56de\u8def\u3078\u306e\u7570\u8ad6  8"},"content":{"rendered":"\n<p>\u3000\u6b74\u53f2\u7684\u306a\u8996\u5ea7\u304b\u3089\u773a\u3081\u308b\u3068\u8272\u3005\u306a\u7591\u554f\u304c\u6b8b\u3063\u3066\u3044\u308b\u3002TCA \u56de\u8def\u306f\u3001\u3044\u3064\u5730\u7403\u4e0a\u306b\u73fe\u308c\u305f\u306e\u3060\u308d\u3046\uff1f\u521d\u3081\u3066\u51fa\u73fe\u3057\u305fTCA\u56de\u8def\u306f\u3001\u73fe\u5728\u306e\u7cfb\u8def\u3068\u540c\u3058\u3082\u306e\u3067\u3042\u3063\u305f\u3060\u308d\u3046\u304b\uff1f\u305d\u308c\u3068\u3082\u3001\u4e0d\u5b8c\u5168\u306a\u7cfb\u3067\u3042\u3063\u305f\u306e\u3060\u308d\u3046\u304b\uff1f TCA \u56de\u8def\u304c\u597d\u6c17\u6761\u4ef6\u4e0b\u3067\u50cd\u304f\u7cfb\u8def\u3067\u3042\u308b\u306a\u3089\u3070\u3001\u5acc\u6c17\u7684\u6761\u4ef6\u4e0b\u3067\u751f\u304d\u308b\u751f\u7269\u306b\u306fTCA\u56de\u8def\u306f\u5b58\u5728\u3059\u308b\u306e\u3060\u308d\u3046\u304b\u3001\u305d\u308c\u3068\u3082\u5b58\u5728\u3057\u306a\u3044\u306e\u3067\u3042\u308d\u3046\u304b\uff1f\u524d\u56de\u306e\u7d42\u308f\u308a\u306b\u305d\u3046\u66f8\u3044\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u3053\u3046\u3057\u305f\u5f62\u306e\u7591\u554f\u3092\u6301\u3064\u5b66\u751f\u306f\u6975\u304f\u5c11\u6570\u3067\u306f\u3042\u308b\u304c\u5b58\u5728\u3059\u308b\u3002\u79c1\u3082\u305d\u3046\u3060\u3063\u305f\u3002\u5f7c\u3089\u306f\u5b8c\u5168\u306a\u5f62\u3067\u306e\u7b54\u3048\u3092\u6c42\u3081\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u305f\u3060\u7d20\u6734\u306b\u7591\u554f\u3092\u51fa\u3057\u3066\u3044\u308b\u306b\u904e\u304e\u306a\u3044\u3002\u6559\u3048\u308b\u5074\u304c\u3001\u305d\u3053\u306f\u79c1\u306b\u3082\u5206\u304b\u3089\u306a\u3044\u3068\u7d20\u76f4\u306b\u7b54\u3048\u308c\u3070\u3001\u3042\u3042\u5148\u751f\u306b\u3082\u308f\u304b\u3089\u306a\u3044\u3053\u3068\u304c\u3042\u308b\u3093\u3060\u3068\u60aa\u6c17\u306e\u6b20\u7247\u3082\u306a\u304f\u559c\u3073\u3001\u305d\u306e\u5148\u751f\u3092\u8efd\u8511\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u5c0a\u656c\u3057\u59cb\u3081\u308b\u5834\u5408\u304c\u3042\u308b\u306e\u3067\u3042\u308b\u3002\u305d\u3057\u3066\u3001\u3053\u308c\u3092\u5951\u6a5f\u306b\u5b66\u554f\u3092\u59cb\u3081\u308b\u5b66\u751f\u3082\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u3000\u3053\u3053\u3067\u5148\u751f\u65b9\u304c\u9762\u5b50\u3068\u6cbd\u5238\u306b\u56da\u308f\u308c\u308b\u3068\u5b66\u751f\u3068\u306e\u4fe1\u983c\u95a2\u4fc2\u304c\u5931\u308f\u308c\u3001\u53d6\u308a\u8fd4\u3057\u306e\u3064\u304b\u306a\u3044\u3053\u3068\u306b\u306a\u308b\u3002\u4eca\u306b\u306a\u3063\u3066\u308f\u304b\u308b\u306e\u3060\u304c\u3001\u5148\u751f\u3068\u3044\u3046\u4eba\u3005\u304c\u6559\u79d1\u66f8\u3092\u4f7f\u3063\u3066\u6559\u3048\u308b\u3053\u3068\u306a\u3069\u5927\u3057\u305f\u4e8b\u3067\u306f\u306a\u3044\u3002\u793e\u4f1a\u306b\u51fa\u3066\u3055\u307b\u3069\u5f79\u7acb\u3064\u7269\u3067\u306f\u306a\u3044\u3057\u3001\u65b0\u3057\u3044\u3068\u3044\u3048\u308b\u5185\u5bb9\u3067\u3082\u306a\u3044\u3002\u5f79\u7acb\u3064\u3068\u3059\u308c\u3070\u3001\u524d\u306b\u9032\u3082\u3046\u3068\u3059\u308b\u5e2b\u306e\u5f8c\u308d\u59ff\u304f\u3089\u3044\u304b\u306a\u3002\u5b66\u751f\uff08\u5f1f\u5b50\uff09\u306b\u306f\u3001\u5e2b\u3092\u8996\u754c\u306e\u5148\u306b\u5728\u308b\u3082\u306e\u3092\u7406\u89e3\u3057\u305d\u308c\u3092\u8d85\u3048\u3088\u3046\u3068\u6c57\u3059\u308b\u614b\u5ea6\u304c\u6c42\u3081\u3089\u308c\u308b\u3002\u3053\u306e\u969b\u3001\u5e2b\u306f\u305d\u3046\u3057\u305f\u3053\u3068\u304c\u3067\u304d\u308b\u5f1f\u5b50\u3092\u5ac9\u3093\u3067\u306f\u306a\u3089\u306a\u3044\u3002<\/p>\n\n\n\n<p>\u3000\u3055\u3066\u672c\u8ad6\u306b\u623b\u308b\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u306b\u793a\u3059\u3053\u308c\u3089\u306e\u56f3\u306f\u3001\u3044\u3064\u3082\u306e\u3088\u3046\u306bKEGG\u306e\u30b5\u30a4\u30c8\u304b\u3089\u306e\u5f15\u7528\u3067\u3042\u308b\u3002\u56f33-16\u306f\u5149\u5408\u6210\u7d30\u83cc\u3067\u3042\u308b<em>Chlorobium chlorochromatii<\/em>\u306e\u6301\u3064 \u56de\u8def\u3001\u56f33-17\u306f\u5acc\u6c17\u6027\u53e4\u7d30\u83cc\u3067\u3042\u308b<em>Thermoproteus uzoniensis<\/em>\u306e\u6301\u3064 \u56de\u8def\u3001\u56f33\u221218\u306f\u597d\u6c17\u6027\u53e4\u7d30\u83cc\u3067\u3042\u308b<em>Sulfolobus tokodaii<\/em>\u306e\u6301\u3064\u56de\u8def\u3001\u305d\u3057\u3066\u56f33\u221219\u304c<em>Homo sapiens (Human)<\/em> \u6301\u3064 TCA\u56de\u8def\u3068\u547c\u3070\u308c\u308b\u7cfb\u8def\u3067\u3042\u308b\u3002\u7cfb\u3092\u52d5\u304b\u3059\u9175\u7d20\u306b\u3044\u304f\u3064\u304b\u306e\u5dee\u7570\u306f\u3042\u308b\u306b\u3057\u3066\u3082\u3001\u7cfb\u3092\u69cb\u6210\u3059\u308b\u5316\u5408\u7269\u306f\u540c\u3058\u3067\u3042\u308a\u3001\u8a3b\u91c8\u306a\u3057\u306b\u3053\u308c\u3089\u306e\u56f3\u3092\u898b\u305b\u3089\u308c\u3066\u3001\u30d2\u30c8\u306e\u6301\u3064\u7cfb\u8def\u3068\u30d2\u30c8\u4ee5\u5916\u306e\u751f\u7269\u304c\u6301\u3064\u7cfb\u8def\u304c\u540c\u3058\u5b58\u5728\u610f\u7fa9\u3092\u6301\u3064\u3082\u306e\u3067\u306f\u306a\u3044\u3068\u4e3b\u5f35\u3059\u308b\u4eba\u304c\u3044\u308b\u3068\u3057\u305f\u3089\u3001\u305d\u306e\u4eba\u306f\u304b\u306a\u308a\u306a\u5909\u4eba\u3060\u3068\u8a8d\u5b9a\u3055\u308c\u3066\u3082\u4ed5\u65b9\u306a\u3044\u3002\u79c1\u3082\u3001\u9577\u3044\u9593\u540c\u3058\u3088\u3046\u306b\u898b\u3048\u3066\u3044\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-16.png\" alt=\"\" class=\"wp-image-7854\" width=\"671\" height=\"511\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-16.png 980w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-16-300x228.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-16-768x585.png 768w\" sizes=\"auto, (max-width: 671px) 100vw, 671px\" \/><figcaption>\u56f33-16\u3000\u5149\u5408\u6210\u7d30\u83cc\u3067\u3042\u308b<em>Chlorobium chlorochromatii<\/em>\u306e\u6301\u3064 \u56de\u8def<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"981\" height=\"733\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-17.png\" alt=\"\" class=\"wp-image-7855\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-17.png 981w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-17-300x224.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-17-768x574.png 768w\" sizes=\"auto, (max-width: 981px) 100vw, 981px\" \/><figcaption>\u56f33-17\u3000\u5acc\u6c17\u6027\u53e4\u7d30\u83cc\u3067\u3042\u308b<em>Thermoproteus uzoniensis<\/em>\u306e\u6301\u3064 \u56de\u8def<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"959\" height=\"724\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-18.png\" alt=\"\" class=\"wp-image-7856\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-18.png 959w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-18-300x226.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-18-768x580.png 768w\" sizes=\"auto, (max-width: 959px) 100vw, 959px\" \/><figcaption>\u56f33-18\u3000\u597d\u6c17\u6027\u53e4\u7d30\u83cc\u3067\u3042\u308b<em>Sulfolobus tokodaii<\/em>\u306e\u6301\u3064\u56de\u8def<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"961\" height=\"719\" src=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-19.png\" alt=\"\" class=\"wp-image-7857\" srcset=\"https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-19.png 961w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-19-300x224.png 300w, https:\/\/bamboolab.yamasatoagr.com\/wp\/wp-content\/uploads\/2022\/11\/3-19-768x575.png 768w\" sizes=\"auto, (max-width: 961px) 100vw, 961px\" \/><figcaption>\u56f33-19\u3000<em>Homo sapiens (Human)<\/em> \u6301\u3064 \u56de\u8def<\/figcaption><\/figure>\n\n\n\n<p>\u3000\u3068\u306f\u3044\u3046\u3082\u306e\u306e\u3001\u7b54\u3048\u308b\u306e\u304c\u751a\u3060\u96e3\u3057\u3044\u56f0\u3063\u305f\u4e8b\u5b9f\u304c\u5b58\u5728\u3059\u308b\u3002\u30d2\u30c8\u3092\u9664\u304f\u4e0a\u8a18\u306e3\u7a2e\u306e\u751f\u7269\u306b\u304a\u3044\u3066\u3001\u305d\u306e TCA \u56de\u8def\u306f\u53f3\u56de\u308a\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u304f\u5de6\u56de\u308a\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u306e\u3067\u3042\u308b\u3002\u3067\u306f\u3001\u305d\u306e\u5de6\u56de\u308a\u306e\u7cfb\u306f\u4f55\u3092\u3057\u3066\u3044\u308b\u306e\u304b\u3002\u56f33\u22122\u3092\u53c2\u7167\u3059\u308c\u3070\u3059\u3050\u306b\u5206\u304b\u308b\u3053\u3068\u3060\u304c\u3001TCA \u56de\u8def\u304c\u5de6\u56de\u308a\u306b\u6a5f\u80fd\u3059\u308b\u3068\u3059\u308c\u3070\u3001\u30b9\u30af\u30b7\u30cb\u30ebCoA \u304b\u30892-Oxoglutarate\u30012-Oxoglutarate\u304b\u3089\u30aa\u30ae\u30b6\u30ed\u30b3\u30cf\u30af\u9178\u306e\u6bb5\u968e\u3067\u70ad\u7d20\u56fa\u5b9a\u304c\u8d77\u3053\u3063\u3066\u3044\u308b\u306e\u3067\u3042\u308b\u3002\u3042\u308b\u7a0b\u5ea6\u4ee5\u4e0a\u306e\u77e5\u8b58\u3092\u6301\u3064\u4eba\u3005\u306f\u3053\u306e\u7cfb\u3092\u77e5\u3063\u3066\u304a\u308a\u3001\u3053\u306e\u9006\u5468\u308a\u306e\u7cfb\u3092\u9084\u5143\u7684\u30af\u30a8\u30f3\u9178\u30b5\u30a4\u30af\u30eb\u3068\u547c\u3093\u3067\u3044\u308b\u3002\u89e3\u7cd6\u7cfb\u3068\u3044\u3046\u7cd6\u306e\u5206\u89e3\u7cfb\u306b\u3001\u7cd6\u65b0\u751f\u7cfb\u3068\u3044\u3046\u9006\u5411\u304d\u306e\u30d9\u30af\u30c8\u30eb\u3092\u6301\u3064\u4ee3\u8b1d\u7cfb\u304c\u5b58\u5728\u3057\u305f\u3088\u3046\u306b\u3001TCA \u56de\u8def\u306b\u3082\u9084\u5143\u7684\u30af\u30a8\u30f3\u9178\u30b5\u30a4\u30af\u30eb\u3068\u3044\u3046\u9006\u5411\u304d\u306e\u30d9\u30af\u30c8\u30eb\u3092\u6301\u3064\u4ee3\u8b1d\u7cfb\u304c\u4f75\u5b58\u3057\u3066\u3044\u308b\u306e\u3067\u3042\u308b\u3002\u3067\u306f\u3053\u306e\u9084\u5143\u7684\u30af\u30a8\u30f3\u9178\u30b5\u30a4\u30af\u30eb\u3068\u3044\u3046\u9006\u5411\u304d\u306e\u30d9\u30af\u30c8\u30eb\u3092\u6301\u3064\u4ee3\u8b1d\u7cfb\u306f\u4f55\u3092\u3057\u3066\u3044\u308b\u306e\u304b\u3002<\/p>\n\n\n\n<p>\u3000\u65e5\u672c\u5149\u5408\u6210\u5b66\u4f1a\u304c2015\u5e744\u6708\u306b\u516c\u958b\u3057\u305fWeb\u7248\u306e\u5149\u5408\u6210\u4e8b\u5178\u3068\u3044\u3046\u30b5\u30a4\u30c8\u304c\u3042\u308b\u3002\u305d\u306e\u4e2d\u304b\u3089\u9084\u5143\u7684\u30af\u30a8\u30f3\u9178\u30b5\u30a4\u30af\u30eb\u3068\u3044\u3046\u9006\u5411\u304d\u306e\u30d9\u30af\u30c8\u30eb\u3092\u6301\u3064\u4ee3\u8b1d\u7cfb\u306b\u3064\u3044\u3066\u306e\u8aac\u660e\u3092\u5f15\u7528\u3057\u305f\u3044\u3002\u4ee5\u4e0b\u3000\u5f15\u7528\u3067\u3042\u308b\u3002\uff08https:\/\/photosyn.jp\/pwiki\/index.php?\u9084\u5143\u7684TCA\u56de\u8def\uff09<\/p>\n\n\n\n<p>\u3000<em>\u300c \u9084\u5143\u7684\u30ab\u30eb\u30dc\u30f3\u9178\u56de\u8def\uff0c\u9006\u8ee2\u30af\u30ec\u30d6\u30b9\u56de\u8def\u3068\u3082\u547c\u3070\u308c\u308b\u70ad\u7d20\u540c\u5316\u56de\u8def\uff0e Evans\u3089(1966)\u306b\u3088\u308a\u7dd1\u8272\u786b\u9ec4\u7d30\u83ccChlorobium 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